Mark Anderson, M.D., director of the Department of Medicine and physician-in-chief of The Johns Hopkins Hospital, has focused his research on the role of the protein CaMKII (Ca2+/calmodulin dependent kinase II) in heart failure and cardiac arrhythmias. In recent years, he and his lab have shown that increased CaMKII activity increases oxidative damage to the cardiovascular system and promotes other chronic conditions. They have identified cellular oxidation sites that they believe to be markers of the aging process, and ultimately hope to provide insights into how oxidant stress contributes to the diseases of aging.

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